It is in human DNA to travel. While some stay where they were planted ideas and growth as a culture come from moving on and up-- or down. At different times it has been on foot and in search of better hunting grounds or maybe out of fear of what had moved into the area. If they wanted more than what could be carried on their backs, humans have used wagons, carts, travoises, or a pack animal. Heavier items had to be left behind. For Native Americans grinding stones would be stashed to return and use for another season. Most recently, we've seen this happening across the world as people leave regions they find less hospitable and hope for a better life elsewhere.

Not all travel then or now has been permanent. Humans go on vacations, explore new regions, and some take roadtrips. In modern times, innovations have allowed us to take more with us-- in fact, everything. Modern homes on the road can have the same luxuries possible at home-- just less of them. Some are making motor coaches, trailers, etc. into full-time homes as they move around the country for jobs or just exploring. With the use of solar panels, heat, refrigeration, or cooling even in the middle of the wilderness, modernity is possible.
